Dr. Grossman’s Blog

Although open-angle glaucoma (OAG) has been previously associated with some of the risk factors of stroke development, researchers at the Taipei Medical University in Taipei, Taiwan have now linked OAG with an increased risk of stroke development.

Researchers collected data from the 1,073,891 subjects in the Taiwan National Health Insurance Research Database.  They compared 4032 patients with a diagnosis of OAG to 20,160 patients without OAG over a five year period.

Of the group of patients with OAG, 14.9% had strokes within the 5-year follow-up period, compared with 9.5% of patients in the comparison group.   After adjusting for patients’ demographic characteristics, patients with OAG were found to have a 1.52-fold higher risk of having a stroke than the matched comparison cohort.

Study authors concluded that patients with OAG demonstrated a significantly increased risk of stroke development during the 5-year follow-up period.

Learn more about glaucoma including self-help tips

Read other studies about glaucoma

SOURCE:  “Open-Angle Glaucoma and the Risk of Stroke Development. A 5-Year Population-Based Follow-Up Study”, Ho, et al, PubMed, 2009 May 21, http://www.ncbi.nlm.nih.gov/pubmed/19461039

Researchers at the University of Western Australia recently examined the effects of wearing swimming goggles upon intraocular pressure (IOP).

In this study, holes were drilled into the faces of 13 different goggles to allow IOP measurement by applanation tonometry. IOP was measured before goggles wear, two minutes after goggles application, twenty minutes after goggles application, and after goggles removal. Multiple types of goggles were tested.

IOP increased while wearing goggles by a mean pressure of 4.5 mm Hg with this pressure rise being sustained for the duration of goggles wear. Swim goggles with a smaller face area were consistently associated with greater IOP elevation.

Although these measurements were not taken while swimming, study authors suggest that some swimming goggles can elevate IOP. The full article can be read in the British Journal of Ophthalmology.

Learn more about natural eye care at www.naturaleyecare.com

NaturalEyeCare™ provides a practical approach to keeping your eyes healthy, emphasizing prevention rather than cure, based on the latest scientific research.

SOURCE: “Wearing swimming goggles can elevate intraocular pressure”, Morgan, et al, Br J Ophthalmol. 2008 Sep;92(9):1218-21.

Seniors who perform poorly on tests of language, memory and concentration are more likely to be suffering from the early stages of age-related macular degeneration (AMD). 

A new study published in the Archives of Ophthalmology reviews the association between cognitive function decline and the onset of AMD.

“We found that those who have memory impairment were more likely to have early stages of macular degeneration independent of the effects of age, education and vascular risk factors,” said study co-author Dr. Tien Yin Wong, a professor in the department of ophthalmology with the Centre for Eye Research Australia at the University of Melbourne.

2088 participants aged 69 to 97 years who participated in the Cardiovascular Health Study were assessed for AMD.  Cognitive function was evaluated using the Digit Symbol Substitution Test (DSST) and the Modified Mini-Mental State Examination. Participants were also evaluated for dementia using detailed neuropsychological testing.

After controlling for age, sex, race, and study center, participants with low DSST scores were more likely to have early AMD than were participants with higher DSST scores.   In analysis that also controlled for education, systolic blood pressure, total cholesterol level, diabetes mellitus, smoking status, and apolipoprotein E genotype, the association was even stronger.

There was no association of dementia or Alzheimer disease with early AMD.

Read other studies on AMD

See tips on preventing vision problems with a focus on nutrition, exercise, lifestyle changes, and a positive mental approach to life at Natural Eye Care

SOURCE:  Early Age-Related Macular Degeneration, Cognitive Function, and Dementia – The Cardiovascular Health Study, Baker, et al, Arch Ophthalmol. 2009;127(5):667-673.

Researchers have released a new study showing that regular consumption of fish, omega-3 polyunsaturated fatty acids, and nuts helps protect against age-related macular degeneration (AMD).

The study, published in the Archives of Ophthalmology, assessed the relationship between dietary fatty acids and the 10-year incident of AMD.

Scientists examined 3654 elderly Australian participants at baseline and re-examined 2454 of these participants five and/or ten years later.  Participants completed a food frequency questionnaire.

The findings confirmed many previous studies on AMD.  After adjusting for age, sex, and smoking:

• one serving of fish per week was associated with reduced risk of early AMD primarily among participants with less than the median linoleic acid consumption
• findings were similar for consumption of long-chain omega-3 polyunsaturated fatty acids:  one to two servings of nuts per week was associated with reduced risk of early AMD 
• protective associations between nut consumption and reduced risk of pigmentary abnormalities were seen among nonsmokers, participants with less than the median ratio of serum total to high-density lipoprotein cholesterol, and those with beta carotene intake greater than the median level.

This study provides evidence of protection against early AMD through:

• regular consumption of fish and nuts
• greater consumption of omega-3 polyunsaturated fatty acids
• low intakes of foods rich in linoleic acid

Read more about AMD and natural eye care

Learn which foods to eat to help maintain good eye health

SOURCE:  Dietary Fatty Acids and the 10-Year Incidence of Age-Related Macular Degeneration, The Blue Mountains Eye Study, Tan, et al, Arch Ophthalmol. 2009;127(5):656-665.

A team of scientists and surgeons from the Institute of Ophthalmology at University College London and the Moorfields Eye Hospital in London has developed a stem cell therapy to treat age-related macular degeneration (AMD), the most common cause of vision loss in the elderly.
“Under the new treatment, embryonic stem cells are transformed into replicas of the missing cells,” writes The Times of London. “They are then placed on an artificial membrane which is inserted in the back of the retina.”

Pharmaceutical giant Pfizer announced this week that it will fund the development of the therapy; UCL professor Pete Coffey, who led the research team, predicts the therapy will be available as part of a simple, one-hour procedure within six or seven years.The researchers are applying for approval to conduct a clinical trial on humans; it would be just the second-ever trial conducted on humans using embryonic stem cells. Laboratory trials completed by the British team have demonstrated that stem cells can prevent blindness in rats with a similar disease to AMD. They have also successfully tested elements of the technology in pigs.

For natural approaches to help prevent the onset of macular degeneration as well as help preserve vision for those with macular degeneration, visit the Natural Eye Care web site

Researchers from Tufts University have found that a diet rich in omega-3 fatty acids and low in starchy carbohydrates can significantly reduce the risk of age-related macular degeneration (AMD).

The study, published in the journal Ophthalmology, is the first to calculate the combined effect of specific dietary nutrients and eating habits on a person’s risk for age-related macular degeneration.

During the study of 4003 participants in the ongoing Age-Related Eye Disease Study (AREDS), each dietary factor was assigned a percentile score; these scores were accumulated to find each participant’s compound score. The compound score was then evaluated for its association with the risk of AMD.

Researchers showed that vitamins C and E, zinc, lutein, zeaxanthin and the omega-3 fatty acids known as D.H.A. and E.P.A. were linked to lower risk for AMD.

The lowest risk of AMD was found in participants who regularly consumed a combination of these nutrients as part of a low-glycemic index diet.

The glycemic index (GI) is a measure of the effects of carbohydrates on blood glucose levels. Carbohydrates that break down rapidly during digestion, such as white bread and pastries, have a higher GI, as they release glucose into the bloodstream rapidly. Foods that break down more slowly, such as vegetables and proteins, have a lower GI value.

Read more about AMD on the Natural Eye Care website

Learn more about food sources for nutrients important for good eye health, including omega-3 fatty acids

SOURCE: “Dietary Compound Score and Risk of Age-Related Macular Degeneration in the Age-Related Eye Disease Study”, Chiu, et al, Ophthalmology, Volume 116, Issue 5, Pages 939-946.