Scientists have long known that our diets influence our risk of age-related macular degeneration (AMD). High glycemic-index diets have now been identified as a risk factor for AMD by researchers from the University of Sydney and the University of Melbourne in Australia, and the National University of Singapore.
The glycemic index (GI) is a measure of the effects of carbohydrates on blood glucose levels. Carbohydrates that break down rapidly during digestion releasing glucose rapidly into the bloodstream have a high GI; carbohydrates that break down slowly, releasing glucose gradually into the bloodstream, have a low GI.
Scientists examined the association between the dietary glycemic index and the incidence of AMD in the Blue Mountain Eye Study population.
During 1992–1994, 3654 people aged 49 years or older attended baseline examinations. Of these, 2335 patients were reexamined after 5 years and 1952 were examined again after 10 years. At each examination, lens photography was performed and food-frequency questionnaires were administered. An Australian database was used to calculate the mean glycemic index.
Over 10 years, 208 of 1810 participants developed early AMD. After adjusting for age, smoking, and other risk factors, a higher mean dietary glycemic index was associated with an increased risk of early AMD.
Conversely, a greater consumption of predominantly lower glycemic index foods was associated with a reduced risk of incident early AMD. No relation was observed with late AMD.
Researchers concluded that a high-glycemic-index diet is a risk factor for early AMD, but they also noted that low glycemic-index foods such as oatmeal may protect against early AMD.
Learn more about the glycemic index and use a free GI database to find the GI index of your favorite carbohydrates at this University of Sydney Glycemic Index web site
SOURCE: Kaushik, et al, Dietary glycemic index and the risk of age-related macular degeneration, American Journal of Clinical Nutrition, Vol. 88, No. 4, 1104-1110, October 2008.