Dr. Grossman’s Blog

MicroCurrent Stimulation (MCS) is an enhanced adaptation of a FDA approved therapy used by anesthesiologists, orthopedic surgeons, plastic surgeons and rehabilitative specialists to promote the healing of wounds and transplanted tissues as well as to treat pain.

The theory is that MCS helps

1. re-stimulate and energize dormant retinal cells (cells are like batteries — when they run low in energy, they become sluggish and dormant),
2. boost the cells’ ability to rid themselves of waste products which interferes with the flow of energy, nutrients and communication,
3. increase blood supply to the area stimulated. By increasing blood flow to the area, cells and tissues still living can get nourished and refreshed.

Research suggests that microcurrent electrical stimulation device approximates the level of electrical activity present in a healthy eye, resulting in stimulating retinal activity and energizing dormant cells, as well as improving microvascular circulation, nerve conduction and velocity.

Microcurrent stimulation increases ATP (energy) synthesis in the retinal cells needed for membrane viability and waste management (a major concern for those with dry macular degeneration as excess waste not reabsorbed and eliminated results in waste accumulation called “drusen”).

Macular Degeneration and Retinitis Pigmentosa are treated with very precise amounts of tightly controlled electrical current through electrodes applied to the skin at specific areas around the eye. The electrical current is used to stimulate the retina as well as the diseased macula in order to help protect sight. The procedure is safe, noninvasive, and painless and no side effects or adverse reactions have been observed.

For more about MicroCurrent Stimulation, click here.

Two research studies have shown that defects in a gene that is an important regulator of parts of the immune system can significantly increase the risk of the age-related macular degeneration (AMD).  While one group of scientists identified the harmful variation of the gene that was linked to the development of AMD, another group identified a another variant possessed by 20 percent of the population that can actually protect people against AMD. Work is being done to find a way to combat AMD with the help of this particular protective protein.

Source: http://www.technologyreview.com/biomedicine/25386/?ref=rss&a=f

A small study by Japanese researchers demonstrates an increased blood supply to the retina upon stimulation of certain acupuncture points. Needles were inserted near the posterior base of the thumbs of volunteers while investigators used a laser to scan the retinal blood flow. Both volume and velocity increased in these patients. The work was done at the ophthalmology department at Kyoto Prefectural University of Medicine.

Reported by Dr. Kazuhiko Mori at the annual meeting of the Association for Vision and Ophthalmology in Fort Lauderdale this past May.

For more related information on natural eye care, go to www.naturaleyecare.com

A new study shows that when people with retinal disease such as macular degeneration use a peripheral part of their retina to compensate for their loss of central vision, their brain appears to compensate by reorganizing its neural connections.

Macular degeneration (MD) causes a progressive loss of central visual.  To cope with this, MD patients often start to focus using a functional retinal area in the periphery of their area of vision. This use of a new area of focus may foster cortical reorganization.

Scientists at the Georgia Institute of Technology used functional magnetic resonance imaging (fMRI) to measure brain activity in participants as they performed a series of tests designed to visually stimulate their peripheral regions.  It was determined that when the participants visually stimulated the peripheral retinal locations they increased brain activity in the same areas of the visual cortex that are normally activated when healthy patients focused on objects in their central visual field.

Study authors believe that large-scale cortical reorganization of visual processing occurs in humans in response to retinal disease.  While several other studies have suggested that the brain can reorganize itself, this is the first study to show that this reorganization in patients with retinal disease is related to patient behavior.

Researchers are currently analyzing how long this reorganization takes and whether it can be assisted with low-vision training.

Learn more about macular degeneration

Read about eye exercises for vision fitness

SOURCE: Reorganization of visual processing is related to eccentric viewing in patients with macular degeneration, Schumacher, et al, Restorative Neurology and Neuroscience, Volume 26, Number 4-5, 2008, 391 – 402.

Scientists through the US Department of Energy are testing artificial retinas that they hope can restore partial sight to people who’ve lost their vision to the most common causes of blindness.

The Sylmar, Calif., company produced the devices for the U.S. Energy Department’s Artificial Retina Project. The department has been engaged in biological research since the atomic bomb tests of the 1950s raised fears of radiation poisoning.

The current version is being tested on 17 blind people in the U.S. and Europe, and more patients are being enrolled. At a retina conference in October, patients reported improvements in orientation and mobility. They were able to find a door from 20 feet away and to follow a line on the floor for 20 feet.

Meanwhile, researchers in the Energy Department’s National Laboratories are creating a third-generation artificial retina. Much smaller than its predecessors, the device will contain 200 or more electrodes on a thin, flexible film that curves to fit the shape of the retina. Human tests are scheduled to begin in 2011.

For more information, go to http://artificialretina.energy.gov/index.shtml

For more information and specific research studies by eye condition including nutrition and vision research, go to <a href=”http://www.naturaleyecare.com”>Natural Eye Care </a>

U.S. researchers found that antioxidants disrupt a link between two processes in the retina that, in combination, contribute to macular degeneration. Antioxidants also extend the lifetime of irreplaceable photoreceptors and other retinal cells.

The “destructive synergy” that causes macular degeneration occurs when a buildup of a compound called A2E disrupts energy production in mitochondria, the “power plants” in cells, the researchers said. The lack of energy interferes with daily cleaning and maintenance of photoreceptors and another type of retinal cell. This leads to more buildup of A2E and a continuing cycle that results in the destruction of the vital visual cells that can’t be replaced.

The study was published online in the Journal of Biological Chemistry.

For more information and specific research studies by eye condition on nutrition and vision, go to <a href=”http://www.naturaleyecare.com”>Natural Eye Care for Macular Degeneration</a>

The findings provide hope for treating blindness caused by optic-nerve damage, but
also look promising for spurring similar regeneration in the spinal cord and brain.
Researchers said Monday a newly discovered growth factor could hold the key to regenerating damaged optic nerves — and more. The research team at Children’s Hospital in Boston say they have found a naturally occurring, previously unrecognized growth factor that stimulates regeneration in injured optic nerves.
The findings provide hope for treating blindness caused by optic-nerve damage, but
also look promising for spurring similar regeneration in the spinal cord and brain,
they said.

The growth factor is called oncomodulin and when it was added to retinal nerve cells
in the lab, with known growth-promoting factors already present, the growth of axons
– or cells in the optic nerves — nearly doubled.

No other growth factor was as potent, the researchers said.

More Nerve Regeneration

In live rats with optic-nerve injury, oncomodulin released from tiny sustained-release
capsules increased nerve regeneration five- to seven-fold when given along with
a drug that helps cells respond to oncomodulin, the team said.

Oncomodulin also appears to switch on a variety of genes associated with axon growth,
the researchers said.

“Out of the blue, we found a molecule that causes more nerve regeneration than
anything else ever studied,” said one of the study investigators. We expect
this to spur further research into what else oncomodulin is doing in the nervous
system and elsewhere.

The data are published in the May 14 online edition of Nature Neuroscience.

For more related research, go to www.naturaleyecare.com (see “Research” section).

FRIDAY, Aug. 29 (HealthDay News) — Eating plenty of antioxidant-rich food such as blueberries, artichokes and pecans may help protect against macular degeneration, the leading cause of age-related blindness in the United States and other developed countries.

U.S. researchers found that antioxidants disrupt a link between two processes in the retina that, in combination, contribute to macular degeneration. Antioxidants also extend the lifetime of irreplaceable photoreceptors and other retinal cells.

The “destructive synergy” that causes macular degeneration occurs when a buildup of a compound called A2E disrupts energy production in mitochondria, the “power plants” in cells, the researchers said. The lack of energy interferes with daily cleaning and maintenance of photoreceptors and another type of retinal cell. This leads to more buildup of A2E and a continuing cycle that results in the destruction of the vital visual cells that can’t be replaced.

Experiments using visual cells from humans, rats and cows showed that antioxidants could completely counter the damage caused by this process, said the researchers from Brigham Young University and Weill Medical College of Cornell University.

“The implication is that people at risk of macular degeneration could help prevent the disease by consuming antioxidants,” study author Heidi Vollmer-Snarr, a Brigham Young chemist, said in a university news release.

The study was published online in the Journal of Biological Chemistry.

“This work by Dr. Vollmer-Snarr and colleagues ties these two damaging processes together and demonstrates the harm they cause in combination is much more than would be expected,” Dr. Paul Bernstein, of the University of Utah’s Moran Eye Center, said in the news release. “This new knowledge,” added Bernstein, who wasn’t involved in the study, “suggests the possibility of interventions which could prove to be powerful ways to prevent or delay age-related macular degeneration.”

For more related studies, go to the “Research” section as www.naturaleyecare.com

A combination of exposure to blue light from sunlight and inadequate levels of antioxidants in the blood contribute to the development of some forms of the eye disease age-related macular degeneration (AMD), say researchers.

Astrid E. Fletcher, PhD, of the London School of Hygiene & Tropical Medicine, and colleagues measured levels of vitamin C and E, the carotenoids lutein and zeaxanthin, and zinc, in the blood of 4,753 seniors with an average age of 73.2 years. The participants were also questioned about sun exposure, and had photographs taken of their retinas.

Results showed that of the 4,400 participants with complete data, 2% had neovascular AMD, an advanced form of the disease, and 50% had early-stage AMD. Overall, there was no link between blue light exposure and neovascular AMD or early-stage AMD. However, participants with a history of blue light exposure and low blood levels of zeaxanthin, vitamin E, and vitamin C were found to be 3.7-times more likely to develop neovascular AMD.

The researchers conclude: Our results suggest that people in the general population should use ocular protection and follow dietary recommendations for the key antioxidant nutrients.

Posted in Nutrition, Sensory on Thu October 16, 2008

Fletcher AE, Bentham GC, Agnew M.Sunlight Exposure, Antioxidants, and Age-Related Macular Degeneration. Arch Ophthalmol. 2008;126:1396-1403.

For more related studies, see the “Research” section at www.naturaleyecare.com

Last month Archives of Ophthalmology published a meta analysis on omega-3 fatty acid and fish intake and its effect on the prevention of age-related macular degeneration (AMD).

This study identified 274 abstracts, 3 prospective cohort, 3 case-control, and 3 cross-sectional studies.

Using quantitative methods, a high dietary intake of omega-3 fatty acids was associated with a 38% reduction in the risk of late AMD. Fish intake (2x per week) was associated with reduced risk of early and late AMD.

More omega-3 and AMD specific studies need to be conducted to further investigate omega-3¹s effect on AMD.

Ref: Arch Ophthalmol. 2008;126(6):826-833.

For more information on related studies and nutrition, go to www.naturaleyecare.com